SCHEMBL7962888

SCHEMBL7962888

CC(C)Cc1cc2ccc(Br)cc2s1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.36
PPARA Q07869 2/20 0.35
CYP2A6 P11509 4/20 0.34
ADRB2 P07550 1/20 0.34
ASIC3 Q9UHC3 1/20 0.33
LOXL2 Q9Y4K0 1/20 0.33
DPP4 P27487 1/20 0.32
NPC1 O15118 4/20 0.32
RAB9A P51151 4/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
DYRK1A Q13627 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19067620 0.81 HDAC3 (0.42) CYP2A6ADRB2ASIC3LOXL2RAB9A
SCHEMBL17229269 0.79 F2 (0.37) PPARACYP2A6ADRB2ASIC3LOXL2
SCHEMBL1530760 0.78 CYP2A6 (0.37) CYP2A6ADRB2ASIC3LOXL2NPC1
SCHEMBL1530454 0.77 CYP2A6 (0.58) CYP2A6ADRB2ASIC3LOXL2NPC1
SCHEMBL17080670 0.77 CYP2A6 (0.58) CYP2A6ADRB2ASIC3LOXL2NPC1
SCHEMBL13907574 0.77 CYP2A6 (0.36) CYP2A6ADRB2ASIC3LOXL2NPC1
SCHEMBL5962350 0.77 CYP2A6 (0.58) CYP2A6ADRB2ASIC3LOXL2CYP1A2
SCHEMBL28156001 0.77 CYP2A6 (0.40) CYP2A6ADRB2ASIC3LOXL2NPC1
SCHEMBL15980826 0.76 NPSR1 (0.34) PPARACYP2A6ADRB2NPC1RAB9A
SCHEMBL3469764 0.76 PTPN2 (0.46) CYP2A6ADRB2ASIC3LOXL2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3523308-B1 ORGANIC SEMICONDUCTING COMPOUNDS RAYNERGY TEK INC (TW) 2023-09-06 EP disclosed
WO-2001090105-A1 ISOTHIAZOLES AS PESTICIDES SYNGENTA LIMITED (GB) 2001-11-29 WO disclosed