Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 11/20 | 0.74 |
| ▸ | PTGIR | P43119 | 10/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955902 | 0.85 | TBXA2R (0.56) | TBXA2RPTGIRKDM4EALDH1A1MAOA | |
| SCHEMBL7955903 | 0.82 | TBXA2R (0.52) | TBXA2RPTGIRKDM4EALDH1A1MAOA | |
| SCHEMBL7948713 | 0.78 | PTGIR (0.87) | TBXA2RPTGIRKDM4EALDH1A1HPGD | |
| SCHEMBL7958766 | 0.77 | PTGIR (0.84) | TBXA2RPTGIRKDM4EALDH1A1HPGD | |
| SCHEMBL7948964 | 0.76 | PTGIR (0.79) | TBXA2RPTGIRKDM4EALDH1A1HPGD | |
| SCHEMBL7958082 | 0.74 | PTGIR (0.76) | TBXA2RPTGIRKDM4EALDH1A1HPGD | |
| SCHEMBL7959498 | 0.73 | PTGIR (0.76) | TBXA2RPTGIRKDM4EALDH1A1HPGD | |
| SCHEMBL7958818 | 0.73 | PTGIR (0.74) | TBXA2RPTGIRKDM4EALDH1A1HPGD | |
| SCHEMBL7958785 | 0.67 | TBXA2R (0.41) | TBXA2RPTGIRKDM4EALDH1A1MAOA | |
| SCHEMBL7958702 | 0.67 | PTGIR (0.69) | TBXA2RPTGIRKDM4EALDH1A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| US-6043264-A | A THROMBOXANE A2 RECEPTOR ANTAGONIST FOR TREATING HYPERTENSION, THROMBOSIS, ISCHEMIC HEART DISEASES, CIRCULATORY DISEASES, ARTERIOSCLEROSIS, PLATELET FUNCTION DISORDER, HYPERLIPIDEMIA, NEPHRITIS OR ASTHMA | TORAY INDUSTRIES, INC. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |