Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682834 | 0.99 | NPY1R (0.67) | NPY1R | |
| Hydrochloric Acid SCHEMBL7687473 | 0.98 | NPY1R (0.66) | NPY1R | |
| SCHEMBL7692020 | 0.89 | NPY1R (0.70) | NPY1R | |
| Hydrochloric Acid SCHEMBL7684113 | 0.88 | NPY1R (0.63) | NPY1R | |
| Hydrochloric Acid SCHEMBL7686820 | 0.88 | NPY1R (0.64) | NPY1R | |
| SCHEMBL7690623 | 0.88 | NPY1R (0.85) | NPY1R | |
| Hydrochloric Acid SCHEMBL7684440 | 0.88 | NPY1R (0.59) | NPY1R | |
| Hydrochloric Acid SCHEMBL7689400 | 0.88 | NPY1R (0.63) | NPY1R | |
| SCHEMBL7695611 | 0.87 | NPY1R (0.74) | NPY1R | |
| SCHEMBL7696750 | 0.87 | NPY1R (0.65) | NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255494-B1 | SUBSTITUTED BENZIMIDAZOLES USEFUL IN TREATING OR PREVENTING CONDITIONS ASSOCIATED WITH EXCESS OF NEUROPEPTIDE Y (AROUND ARTERIES IN HEART, RESPIRATORY TRACT, GASTROINTESTINAL TRACT AND GENITOURINARY TRACT); ETIOLOGY OF PSYCHIATRIC DISORDERS | ELI LILLY AND COMPANY | 2001-07-03 | — | — | US | disclosed |
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |