⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42070 | 0.95 | — | — | |
| SCHEMBL12570289 | 0.91 | TDP1 (0.40) | — | |
| SCHEMBL10122628 | 0.91 | TDP1 (0.40) | — | |
| Ammonia Solution, Strong SCHEMBL9645049 | 0.91 | — | — | |
| SCHEMBL10122625 | 0.91 | TDP1 (0.40) | — | |
| Hydrochloric Acid SCHEMBL25414584 | 0.91 | — | — | |
| SCHEMBL12570288 | 0.91 | TDP1 (0.40) | — | |
| SCHEMBL7954702 | 0.91 | — | — | |
| SCHEMBL11454029 | 0.91 | — | — | |
| SCHEMBL12570292 | 0.91 | TDP1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100374411-C | Process for preparing racemic or optically active 4- (hydroxymethyl) -2-cyclopentene derivatives | LONZA CO LTD (CH) | 2008-03-12 | — | — | CN | disclosed |
| CN-1302116-C | Process for preparing enantiomers of (1R, 4S) -or (1S, 4R) -1-amino-4- (hydroxymethyl) -2-cyclopentene derivatives | LONZE AG (CH) | 2007-02-28 | — | — | CN | disclosed |
| CN-1827591-A | Process for preparing racemic or optically active 4- (hydroxymethyl) -2-cyclopentene derivatives | LONZA AG (CH) | 2006-09-06 | — | — | CN | disclosed |
| CN-1515673-A | Process for preparing enantiomers of (1R, 4S) -or (1S, 4R) -1-amino-4- (hydroxymethyl) -2-cyclopentene derivatives | ��¡���ӹɷ�����˾ | 2004-07-28 | — | — | CN | disclosed |
| CN-1115343-C | Process for the preparation of (1S,4R) -or (1R,4S) -4- (2-amino-6-chloro-9H-purin-9-yl) -2-cyclopentene-1-methanol or salts thereof | LONZA AG (CH) | 2003-07-23 | — | — | CN | disclosed |
| US-6262295-B1 | REACTING CYCLOPENTENE-4-CARBOXYLIC ACID WITH AN ACYL HALIDE | LONZA A.G. (CH) | 2001-07-17 | — | — | US | disclosed |
| US-6252112-B1 | MIBCROBIAL HYDROLYSIS OF THE TITLE COMPOUND DERIVATIVE USING ENZYME HAVING N-ACETYLAMINO-ALCOHOL HYDROLASE OR PENICILLIN G ACYLASE ACTIVITY WITH SUBSEQUENT ACYLATION | LONZA A.G., (CH) | 2001-06-26 | — | — | US | disclosed |
| US-6156893-A | Process for the preparation of (1S,4R)- or (1R,4S)- 4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol | LONZA A.G. (CH) | 2000-12-05 | — | — | US | disclosed |
| US-6137007-A | CHEMICAL INTERMEDIATES FOR NUCLEOSIDE, 4-2-(AMINO-6-CHLORO-9H-PURIN-9-YL)-2-CYCLOPENTENE-1-METHANOL, WHICH IS AN INTERMEDIATE FOR 6-(CYCLOPROPYLAMINO)-DERIVATIVE | LONZA AG (CH) | 2000-10-24 | — | — | US | disclosed |
| CN-1201794-A | Process for the preparation of (1S,4R) -or (1R,4S) -4- (2-amino-6-chloro-9H-purin-9-yl) -2-cyclopentene-1-methanol or salts thereof | LONZA AG (CH) | 1998-12-16 | — | — | CN | disclosed |