Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.48 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045726 | 0.94 | CYP3A4 (0.71) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL28187385 | 0.91 | LPAR3 (0.65) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL28355563 | 0.90 | CYP3A4 (0.59) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL27546062 | 0.90 | CYP3A4 (0.59) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL28762837 | 0.90 | CYP3A4 (0.59) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL28762820 | 0.90 | CYP3A4 (0.59) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| SCHEMBL28352998 | 0.89 | CYP3A4 (0.63) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| Ammonia Solution, Strong SCHEMBL28762843 | 0.89 | CYP3A4 (0.57) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| Ammonia Solution, Strong SCHEMBL28762838 | 0.89 | CYP3A4 (0.57) | CYP3A4LPAR3LPAR2LPAR1TSHR | |
| Ammonia Solution, Strong SCHEMBL29062197 | 0.87 | CYP3A4 (0.61) | CYP3A4LPAR3LPAR2LPAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37101-E1 | AIRCRAFT HYDRAULIC FLUIDS | SOLUTIA INC. | 2001-03-20 | — | — | US | disclosed |
| EP-0644922-B1 | FUNCTIONAL FLUID | MONSANTO CO (US) | 1998-05-13 | — | — | EP | disclosed |
| US-5464551-A | Aircraft hydraulic fluid | MONSANTO COMPANY (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0644922-A1 | FUNCTIONAL FLUID | MONSANTO COMPANY (US) | 1995-03-29 | — | — | EP | disclosed |
| WO-1993025641-A1 | FUNCTIONAL FLUID | MONSANTO COMPANY (US) | 1993-12-23 | — | — | WO | disclosed |