Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.37 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19729247 | 0.81 | SLC22A6 (0.41) | SLC22A6TDP1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL19729246 | 0.77 | SLC22A6 (0.43) | SLC22A6TDP1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL22384141 | 0.77 | SLC22A6 (0.38) | SLC22A6TDP1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL105805 | 0.76 | — | — | |
| SCHEMBL103866 | 0.76 | — | — | |
| SCHEMBL19729262 | 0.75 | SLC22A6 (0.36) | SLC22A6TDP1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL19729271 | 0.75 | TDP1 (0.40) | SLC22A6TDP1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL19729273 | 0.75 | SLC22A6 (0.36) | SLC22A6TDP1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL6435732 | 0.75 | TDP1 (0.40) | SLC22A6TDP1CACNA2D1CACNB3CACNA1C | |
| SCHEMBL7000054 | 0.74 | SLC22A6 (0.39) | SLC22A6TDP1CACNA2D1CACNB3CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104447707-B | Hepatitis c virus inhibitors | 百时美施贵宝公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-103429607-B | There is the triterpenoid that C-17 and C-3 of HIV maturation inhibit activities is modified | BRISTOL-MYERS SQUIBB CO. (US) | 2016-02-17 | — | — | CN | disclosed |
| CN-104447707-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2015-03-25 | — | — | CN | disclosed |
| CN-101558059-B | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2014-12-03 | — | — | CN | disclosed |
| CN-103429607-A | C-17 and C-3 modified triterpenoids with HIV maturation inhibitory activity | BRISTOL MYERS SQUIBB CO | 2013-12-04 | — | — | CN | disclosed |
| CN-102007122-B | Imidazolyl biphenyl imidazoles as hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2013-09-04 | — | — | CN | disclosed |
| CN-102007122-A | Imidazolyl biphenyl imidazoles as hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2011-04-06 | — | — | CN | disclosed |
| CN-101558059-A | Hepatitis C virus inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2009-10-14 | — | — | CN | disclosed |
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |