Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12851363 | 0.76 | HRH3 (0.56) | HRH3LMNATDP1ALDH1A1ALOX15 | |
| SCHEMBL9059102 | 0.73 | HRH1 (0.49) | HRH3LMNATDP1ALDH1A1ALOX15 | |
| SCHEMBL13853783 | 0.73 | CNR1 (0.62) | HRH3LMNATDP1ALDH1A1ALOX15 | |
| SCHEMBL16561480 | 0.73 | SMN1; SMN2 (0.60) | HRH3LMNATDP1ALDH1A1ALOX15 | |
| SCHEMBL21122917 | 0.72 | HRH1 (0.55) | HRH3LMNATDP1ALDH1A1ALOX15 | |
| SCHEMBL3581477 | 0.72 | HRH1 (0.55) | HRH3LMNATDP1ALDH1A1ALOX15 | |
| SCHEMBL375097 | 0.72 | HRH1 (0.55) | HRH3LMNATDP1ALDH1A1ALOX15 | |
| SCHEMBL8282497 | 0.72 | NPC1 (0.57) | HRH3LMNATDP1ALDH1A1ALOX15 | |
| SCHEMBL5499742 | 0.72 | HRH1 (0.59) | HRH3LMNATDP1ALDH1A1ALOX15 | |
| SCHEMBL1032275 | 0.71 | SMN1; SMN2 (0.53) | HRH3LMNATDP1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |