Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.54 |
| ▸ | PTGIR | P43119 | 4/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.54 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 7/20 | 0.40 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
| ▸ | RXRB | P28702 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 2/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959297 | 0.90 | PTGER4 (0.44) | PTGER4PTGIRPTGER1NR4A2RXRA | |
| SCHEMBL7960009 | 0.82 | TDP1 (0.42) | PTGER4PTGIRPTGER1RXRARXRB | |
| SCHEMBL7961262 | 0.82 | PTGIR (0.66) | PTGER4PTGIRPTGER1NR4A2PTGER3 | |
| SCHEMBL7957666 | 0.78 | PTGER4 (0.52) | PTGER4PTGIRPTGER1KMONR4A2 | |
| SCHEMBL7949886 | 0.73 | PTGIR (0.89) | PTGER4PTGIRPTGER1NR4A2PTGER3 | |
| SCHEMBL7958123 | 0.73 | PTGIR (0.89) | PTGER4PTGIRPTGER1NR4A2PTGER3 | |
| SCHEMBL7959822 | 0.72 | PTGIR (0.54) | PTGER4PTGIRPTGER1PTGER3FABP4 | |
| SCHEMBL7959285 | 0.72 | PTGIR (0.83) | PTGER4PTGIRPTGER1NR4A2PTGER3 | |
| SCHEMBL7960373 | 0.71 | PTGIR (0.59) | PTGER4PTGIRPTGER1NR4A2RXRA | |
| SCHEMBL1626140 | 0.70 | PTGIR (1.00) | PTGER4PTGIRPTGER1NR4A2PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245790-B1 | ANTIINFLAMMATORY AGENTS; GASTROINTESTINAL DISORDERS; SKN DISORDERS; BONE DISORDERS; MUSCLE RELAXANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0989975-A1 | OXAZOLE COMPOUNDS USEFUL AS PGE2 AGONISTS AND ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |
| WO-2000016760-A2 | NEW USE OF PROSTAGLANDIN E2 ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-30 | — | — | WO | disclosed |
| WO-1998055468-A1 | OXAZOLE COMPOUNDS USEFUL AS PGE2 AGONISTS AND ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-10 | — | — | WO | disclosed |