Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.46 |
| ▸ | SCN1A | P35498 | 2/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7628352 | 0.83 | CTDSP1 (0.43) | CA1CA2CA9APEX1F2 | |
| SCHEMBL7624190 | 0.83 | PLAU (0.43) | CA1CA2CA9APEX1F2 | |
| SCHEMBL12829322 | 0.83 | CYP1A2 (0.41) | APEX1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL9178147 | 0.81 | TTR (0.58) | APEX1ALDH1A1CYP3A4HSD17B10TSHR | |
| SCHEMBL9040824 | 0.81 | CA1 (0.47) | CA1CA2CA9APEX1F2 | |
| SCHEMBL9097803 | 0.80 | CA1 (0.53) | CA1CA2CA9APEX1F2 | |
| SCHEMBL3708176 | 0.80 | MYC (0.36) | CA1CA2CA9APEX1ALDH1A1 | |
| SCHEMBL9040819 | 0.79 | CA1 (0.46) | CA1CA2CA9APEX1F2 | |
| SCHEMBL9177053 | 0.78 | TTR (0.46) | CA2APEX1 | |
| SCHEMBL8740691 | 0.78 | EPHX2 (0.41) | CA1CA2CA9APEX1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281340-B1 | FIBER REACTIVE DYE | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2001-08-28 | — | — | US | disclosed |
| US-5047515-A | Monoazo Dyes | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| US-3957751-A | WATER-SOLUBLE REACTIVE DYESTUFFS OF THE MONOAZO SERIES CONTAINING AN ACTIVE METHYLENE COUPLING COMPONENT | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |