Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 9/20 | 0.74 |
| ▸ | PTGER4 | P35408 | 5/20 | 0.74 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.74 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.63 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | RXRB | P28702 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959805 | 0.92 | PTGIR (0.66) | PTGIRPTGER4PTGER1PTGER3NR4A2 | |
| SCHEMBL7493262 | 0.89 | PTGIR (0.68) | PTGIRPTGER4PTGER1PTGER3NR4A2 | |
| SCHEMBL8551740 | 0.87 | PTGIR (0.66) | PTGIRPTGER4PTGER1PTGER3NR4A2 | |
| SCHEMBL7491532 | 0.86 | PTGIR (0.68) | PTGIRPTGER4PTGER1PTGER3FABP4 | |
| SCHEMBL7957721 | 0.86 | PTGER4 (0.81) | PTGIRPTGER4PTGER1PTGER3NR4A2 | |
| SCHEMBL7960451 | 0.86 | PTGER4 (0.81) | PTGIRPTGER4PTGER1PTGER3NR4A2 | |
| SCHEMBL8551738 | 0.86 | PTGIR (0.64) | PTGIRPTGER4PTGER1PTGER3NR4A2 | |
| SCHEMBL7490153 | 0.85 | PTGIR (0.64) | PTGIRPTGER4PTGER1PTGER3FABP4 | |
| SCHEMBL1626140 | 0.85 | PTGIR (1.00) | PTGIRPTGER4PTGER1PTGER3NR4A2 | |
| SCHEMBL7960055 | 0.85 | PTGIR (1.00) | PTGIRPTGER4PTGER1PTGER3NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245790-B1 | ANTIINFLAMMATORY AGENTS; GASTROINTESTINAL DISORDERS; SKN DISORDERS; BONE DISORDERS; MUSCLE RELAXANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0989975-A1 | OXAZOLE COMPOUNDS USEFUL AS PGE2 AGONISTS AND ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-05 | — | — | EP | disclosed |
| WO-2000016760-A2 | NEW USE OF PROSTAGLANDIN E2 ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-30 | — | — | WO | disclosed |
| WO-1998055468-A1 | OXAZOLE COMPOUNDS USEFUL AS PGE2 AGONISTS AND ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-10 | — | — | WO | disclosed |