Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.64 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.58 |
| ▸ | CNR1 | P21554 | 5/20 | 0.49 |
| ▸ | CNR2 | P34972 | 5/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809805 | 0.93 | HRH1 (0.57) | HRH1NPY5RCNR1CNR2SCN2A | |
| SCHEMBL7811963 | 0.90 | NPY5R (0.61) | HRH1NPY5RCNR1CNR2SCN2A | |
| Hydrochloric Acid SCHEMBL7815919 | 0.89 | NPY5R (0.60) | HRH1NPY5RCNR1CNR2SCN2A | |
| Hydrochloric Acid SCHEMBL7808457 | 0.89 | NPY5R (0.60) | HRH1NPY5RCNR1CNR2SCN2A | |
| SCHEMBL7808367 | 0.83 | NPY5R (0.58) | HRH1NPY5RCNR1CNR2SCN2A | |
| Hydrochloric Acid SCHEMBL7815764 | 0.82 | NPY5R (0.57) | HRH1NPY5RCNR1CNR2SCN2A | |
| Hydrochloric Acid SCHEMBL7811954 | 0.81 | NPY5R (0.56) | HRH1NPY5RCNR1CNR2SCN2A | |
| SCHEMBL7809800 | 0.80 | NPY5R (0.55) | HRH1NPY5RCNR1CNR2SCN2A | |
| Hydrochloric Acid SCHEMBL7809827 | 0.79 | NPY5R (0.54) | HRH1NPY5RCNR1CNR2SCN2A | |
| Hydrochloric Acid SCHEMBL7812460 | 0.79 | NPY5R (0.54) | HRH1NPY5RCNR1CNR2SCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265426-B1 | CENTRAL NERVOUS SYSTEM DISORDERS | HOFFMANN-LA ROCHE INC. | 2001-07-24 | — | — | US | disclosed |