Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7946856 | 0.95 | BACE1 (0.50) | BACE1 | |
| SCHEMBL7960121 | 0.95 | BACE1 (0.50) | BACE1 | |
| SCHEMBL7964278 | 0.94 | BACE1 (0.55) | BACE1 | |
| SCHEMBL12247415 | 0.91 | BACE1 (0.57) | BACE1 | |
| SCHEMBL7950723 | 0.89 | BACE1 (0.57) | BACE1 | |
| SCHEMBL7949755 | 0.89 | BACE1 (0.56) | BACE1 | |
| SCHEMBL7957663 | 0.89 | BACE1 (0.50) | BACE1 | |
| SCHEMBL12247429 | 0.88 | BACE1 (0.54) | BACE1 | |
| SCHEMBL12247427 | 0.88 | BACE1 (0.54) | BACE1 | |
| SCHEMBL7950154 | 0.88 | BACE1 (0.57) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021680-A2 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. (US) | 2010-02-25 | — | — | WO | disclosed |