Methoxyacetic Acid

Methoxyacetic Acid

SCHEMBL7964609

COCC(=O)O.O=C(O)Cc1cccs1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.47
HPGD P15428 5/20 0.46
ALDH1A1 P00352 2/20 0.46
KMT2A Q03164 5/20 0.46
MEN1 O00255 4/20 0.46
POLB P06746 3/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
RAB9A P51151 2/20 0.46
NPC1 O15118 2/20 0.46
BLM P54132 1/20 0.46
CTDSP1 Q9GZU7 1/20 0.46
MAPK8 P45983 1/20 0.46
MAPK9 P45984 1/20 0.46
MAPK10 P53779 1/20 0.46
PKM P14618 1/20 0.46
USP2 O75604 1/20 0.45
HSD17B10 Q99714 1/20 0.45
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL11407062 0.86 CYP2C19 (0.55) CYP2C19SMN1; SMN2HPGDALDH1A1KMT2A
SCHEMBL621289 0.86
SCHEMBL11405212 0.84 CYP2C19 (0.53) CYP2C19SMN1; SMN2HPGDALDH1A1KMT2A
SCHEMBL28515022 0.84 CYP2C19 (0.57) CYP2C19SMN1; SMN2HPGDALDH1A1KMT2A
Methane SCHEMBL7760510 0.84 CYP2C19 (0.57) CYP2C19SMN1; SMN2HPGDALDH1A1KMT2A
Fluoride SCHEMBL27971505 0.84 CYP2C19 (0.57) CYP2C19SMN1; SMN2HPGDALDH1A1KMT2A
SCHEMBL9285235 0.84 CYP2C19 (0.57) CYP2C19SMN1; SMN2HPGDALDH1A1KMT2A
Hydrochloric Acid SCHEMBL1372448 0.84 CYP2C19 (0.57) CYP2C19SMN1; SMN2HPGDALDH1A1KMT2A
SCHEMBL10484325 0.84 CYP2C19 (0.57) CYP2C19SMN1; SMN2HPGDALDH1A1KMT2A
Benzene SCHEMBL10716512 0.84 CYP2C19 (0.57) CYP2C19SMN1; SMN2HPGDALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6215016-B1 HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA TORAY INDUSTRIES, INC. (JP) 2001-04-10 US disclosed
EP-0841063-A1 KETONE DERIVATIVES AND MEDICINAL USE THEREOF TORAY INDUSTRIES, INC. (JP) 1998-05-13 EP disclosed