Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 14/20 | 0.43 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.42 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963805 | 1.00 | KDM4E (0.44) | KDM4EABCB1ABCC9KCNE1KCNQ1 | |
| SCHEMBL7134039 | 1.00 | KDM4E (0.44) | KDM4EABCB1ABCC9KCNE1KCNQ1 | |
| SCHEMBL7134035 | 1.00 | KDM4E (0.44) | KDM4EABCB1ABCC9KCNE1KCNQ1 | |
| SCHEMBL7952707 | 1.00 | KDM4E (0.44) | KDM4EABCB1ABCC9KCNE1KCNQ1 | |
| SCHEMBL9209930 | 0.83 | KDM4E (0.44) | KDM4EABCB1ABCC9KCNE1KCNQ1 | |
| SCHEMBL7970569 | 0.81 | BCL2 (0.33) | — | |
| SCHEMBL7964901 | 0.81 | BCL2 (0.33) | — | |
| SCHEMBL482186 | 0.80 | KDM4E (0.60) | KDM4EABCB1ABCC9KCNE1KCNQ1 | |
| SCHEMBL8983412 | 0.80 | KDM4E (0.60) | KDM4EABCB1ABCC9KCNE1KCNQ1 | |
| SCHEMBL9260385 | 0.80 | KDM4E (0.60) | KDM4EABCB1ABCC9KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323238-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2001-11-27 | — | — | US | disclosed |