Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3806903 | 0.95 | HTT (0.80) | HTTCYP3A4LMNAHSD17B10TP53 | |
| SCHEMBL5066429 | 0.94 | HTT (0.78) | HTTCYP3A4LMNAHSD17B10TP53 | |
| SCHEMBL5177317 | 0.94 | HTT (0.78) | HTTCYP3A4LMNAHSD17B10TP53 | |
| SCHEMBL28860002 | 0.94 | HTT (0.78) | HTTCYP3A4LMNAHSD17B10TP53 | |
| Hydrochloric Acid SCHEMBL30610402 | 0.91 | HTT (0.74) | HTTCYP3A4LMNAHSD17B10TP53 | |
| SCHEMBL9201457 | 0.90 | HTT (1.00) | HTTCYP3A4LMNAHSD17B10TP53 | |
| SCHEMBL10344722 | 0.86 | HTT (0.69) | HTTCYP3A4LMNAHSD17B10TP53 | |
| SCHEMBL24806440 | 0.84 | HTT (0.67) | HTTCYP3A4LMNAHSD17B10TP53 | |
| SCHEMBL7758793 | 0.83 | HTT (0.76) | HTTCYP3A4LMNAHSD17B10TP53 | |
| SCHEMBL29611420 | 0.83 | HTT (0.76) | HTTCYP3A4LMNAHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5183732-A | Adenine-type grain growth modifier | EASTMAN KODAK COMPANY (US) | 1993-02-02 | — | — | US | claimed |
| WO-2020160174-A1 | USES OF COMPOUNDS HAVING ANTI-HSV-1 ACTIVITY | UNIVERSITA DEGLI STUDI DI PADOVA (IT) | 2020-08-06 | — | — | WO | disclosed |
| WO-2020160175-A1 | QUINDOLINE COMPOUNDS AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2020-08-06 | — | — | WO | disclosed |
| WO-2020061367-A1 | COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| US-20130231307-A1 | NOVEL ANTIVIRAL ACYCLIC NUCLEOSIDE PHOSPHONATES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-09-05 | — | — | US | disclosed |
| EP-2616474-A1 | NOVEL ANTIVIRAL ACYCLIC NUCLEOSIDE PHOSPHONATES | Centre National De La Recherche Scientifique (FR) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012034719-A1 | NOVEL ANTIVIRAL ACYCLIC NUCLEOSIDE PHOSPHONATES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-03-22 | — | — | WO | disclosed |
| EP-0517833-B2 | REGENERATION AND GENETIC TRANSFORMATION OF SUGAR BEET | BAYER BIOSCIENCE NV (BE) | 2008-07-16 | — | — | EP | disclosed |
| EP-0577173-A1 | High-chloride folded tabular grain emulsions and process for their preparation | EASTMAN KODAK COMPANY (US) | 1994-01-05 | — | — | EP | disclosed |
| EP-0534325-A1 | Ultrathin high chloride tabular grain emulsions | EASTMAN KODAK COMPANY (US) | 1993-03-31 | — | — | EP | disclosed |
| US-4086347-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTIEDEMIC AGENTS, HYPOTENSIVES | BOEHRINGER MANNHEIM GMBH (DT) | 1978-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130231307-A1 | NOVEL ANTIVIRAL ACYCLIC NUCLEOSIDE PHOSPHONATES | PNP, TYMP, EIF2AK2 | HTT 3727/4885CYP3A4 3023/4885LMNA 3155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.