Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | HBB | P68871 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1567222 | 0.87 | HTT (0.77) | HTTALDH1A1SMN1; SMN2POLBHPGD | |
| Hydrochloric Acid SCHEMBL11028252 | 0.84 | HTT (0.73) | HTTALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL4553361 | 0.83 | HTT (0.71) | HTTALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL10956812 | 0.80 | HTT (0.66) | HTTALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL1545537 | 0.80 | HTT (0.66) | HTTALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL1568393 | 0.80 | HTT (0.66) | HTTALDH1A1SMN1; SMN2POLBHPGD | |
| Hydrochloric Acid SCHEMBL9118438 | 0.78 | HTT (0.63) | HTTALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL4522017 | 0.77 | HTT (0.63) | HTTALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL1568297 | 0.77 | HTT (0.62) | HTTALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL22393113 | 0.76 | HPGD (0.76) | HTTALDH1A1SMN1; SMN2HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313294-B1 | Process for preparing amides | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2001-11-06 | — | — | US | disclosed |
| US-4301171-A | 2-(1,4-Benzodioxan-2-ylalkyl)benzimidazoles useful as anti-depressants | SYNTEX (U.S.A.) INC. (US) | 1981-11-17 | — | — | US | disclosed |