Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.58 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.58 |
| ▸ | ITGAL | P20701 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CRHBP | P24387 | 2/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27798760 | 0.85 | SMN1; SMN2 (0.68) | ITGB2ICAM1ITGALSMN1; SMN2GAA | |
| Propionic Acid SCHEMBL27896305 | 0.83 | NPC1 (0.44) | SMN1; SMN2GAAATMCTNNB1POLB | |
| Carbamic Acid SCHEMBL8524035 | 0.80 | ITGB2 (0.67) | ITGB2ICAM1ITGALSMN1; SMN2GAA | |
| Methyl Alcohol SCHEMBL3885106 | 0.79 | ITGB2 (0.82) | ITGB2ICAM1ITGALSMN1; SMN2GAA | |
| SCHEMBL5444155 | 0.79 | ITGB2 (0.58) | ITGB2ICAM1ITGALSMN1; SMN2GAA | |
| Benzene SCHEMBL28072178 | 0.79 | ITGB2 (0.93) | ITGB2ICAM1ITGALSMN1; SMN2GAA | |
| Propionic Acid SCHEMBL23466972 | 0.78 | ATM (0.57) | SMN1; SMN2GAAATMLMNAHTT | |
| Propionic Acid SCHEMBL28712698 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2GAAATMLMNAHTT | |
| Propionic Acid SCHEMBL23529449 | 0.78 | ATM (0.43) | SMN1; SMN2GAAATMLMNAHTT | |
| SCHEMBL11406989 | 0.76 | ITGB2 (1.00) | ITGB2ICAM1ITGALSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679370-A | Novel vanilloid receptor ligands and the use thereof for the production of pharmaceuticals | GRUENENTHAL GMBH | 2010-03-24 | — | — | CN | disclosed |
| US-6313294-B1 | Process for preparing amides | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2001-11-06 | — | — | US | disclosed |