Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16662377 | 0.74 | MEN1 (0.43) | ALDH1A1LMNAMEN1KMT2AMAOB | |
| SCHEMBL16652583 | 0.74 | MEN1 (0.43) | ALDH1A1LMNAMEN1KMT2AMAOB | |
| SCHEMBL16652847 | 0.74 | MEN1 (0.43) | ALDH1A1LMNAMEN1KMT2AMAOB | |
| SCHEMBL18857047 | 0.73 | USP2 (0.47) | KDM4ETSHRUSP2ALDH1A1LMNA | |
| SCHEMBL31330287 | 0.73 | CYP3A4 (0.52) | TSHRUSP2ALDH1A1LMNAMEN1 | |
| SCHEMBL20767369 | 0.73 | CYP3A4 (0.52) | TSHRUSP2ALDH1A1LMNAMEN1 | |
| SCHEMBL20767380 | 0.73 | CYP3A4 (0.52) | TSHRUSP2ALDH1A1LMNAMEN1 | |
| SCHEMBL20785827 | 0.73 | CYP3A4 (0.52) | TSHRUSP2ALDH1A1LMNAMEN1 | |
| SCHEMBL31330248 | 0.73 | CYP3A4 (0.52) | TSHRUSP2ALDH1A1LMNAMEN1 | |
| SCHEMBL18258279 | 0.71 | USP2 (0.56) | KDM4ETSHRUSP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001060781-A2 | DIPHENYL COMPOUNDS, FORMULATIONS AND USES THEREOF | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2001-08-23 | — | — | WO | claimed |