Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 13/20 | 0.74 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7684636 | 0.99 | EGLN1 (0.72) | EGLN1RAB9ANPC1SMN1; SMN2GPR55 | |
| SCHEMBL7961819 | 0.88 | EGLN1 (0.69) | EGLN1MEN1KMT2A | |
| SCHEMBL7965470 | 0.87 | EGLN1 (0.79) | EGLN1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7689282 | 0.87 | EGLN1 (0.68) | EGLN1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7688566 | 0.86 | EGLN1 (0.77) | EGLN1ALDH1A1MAPT | |
| SCHEMBL2201326 | 0.86 | EGLN1 (1.00) | EGLN1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL2202554 | 0.84 | EGLN1 (0.80) | EGLN1RAB9ANPC1SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7693361 | 0.83 | EGLN1 (0.79) | EGLN1RAB9ANPC1SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7691643 | 0.81 | EGLN1 (0.76) | EGLN1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL7689924 | 0.81 | EGLN1 (0.76) | EGLN1RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310211-B1 | ANTI-VIRAL ACTIVITY AGAINST HERPES VIRUS, CYTOMEGALOVIRUS. MANY OF THESE COMPOUNDS ARE ALSO ACTIVE AGAINST VARICELLA ZOSTER VIRUS, EPSTEIN-BARR VIRUS, HERPES SIMPLEX VIRUS AND HUMAN HERPES VIRUS TYPE 8 | PHARMACIA & UPJOHN COMPANY | 2001-10-30 | — | — | US | claimed |