Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 6/20 | 0.62 |
| ▸ | JAK2 | O60674 | 14/20 | 0.59 |
| ▸ | JAK3 | P52333 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11916701 | 0.77 | JAK1 (1.00) | JAK1JAK2JAK3 | |
| SCHEMBL2239260 | 0.77 | JAK1 (1.00) | JAK1JAK2JAK3 | |
| SCHEMBL2237181 | 0.76 | JAK1 (0.72) | JAK1JAK2JAK3 | |
| SCHEMBL7963880 | 0.76 | JAK1 (0.65) | JAK1JAK2JAK3 | |
| SCHEMBL2237531 | 0.75 | JAK2 (1.00) | JAK1JAK2JAK3 | |
| SCHEMBL13031259 | 0.74 | JAK1 (0.72) | JAK1JAK2JAK3 | |
| SCHEMBL2244635 | 0.74 | JAK3 (1.00) | JAK1JAK2JAK3 | |
| SCHEMBL13031302 | 0.74 | JAK3 (0.73) | JAK1JAK2JAK3 | |
| SCHEMBL2236844 | 0.73 | JAK3 (1.00) | JAK1JAK2JAK3 | |
| SCHEMBL2243209 | 0.73 | JAK2 (1.00) | JAK1JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010190-A1 | NOVEL COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2010-01-28 | — | — | WO | disclosed |