Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 2/20 | 0.90 |
| ▸ | GRM6 | O15303 | 2/20 | 0.90 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.90 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.90 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.90 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.90 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.90 |
| ▸ | GSR | P00390 | 1/20 | 0.90 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.90 |
| ▸ | GRM5 | P41594 | 1/20 | 0.90 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.90 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.90 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.90 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.90 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.90 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.90 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.90 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.90 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.90 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamic Acid SCHEMBL15231875 | 0.97 | GRM8 (0.95) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL27740981 | 0.97 | GRM8 (0.95) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL9449715 | 0.95 | GRM8 (0.90) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL27721208 | 0.95 | GRM8 (0.90) | GRM8GRM6GRM7GRM4CYP1A2 | |
| Glutamic Acid SCHEMBL639610 | 0.95 | GRM8 (0.90) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL1332297 | 0.95 | GRM8 (1.00) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL1330484 | 0.95 | GRM8 (1.00) | GRM8GRM6GRM7GRM4CYP1A2 | |
| Glutamic Acid SCHEMBL1554237 | 0.95 | GRM8 (1.00) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL1330824 | 0.95 | GRM8 (1.00) | GRM8GRM6GRM7GRM4CYP1A2 | |
| D-Glutamate SCHEMBL17127348 | 0.95 | GRM8 (1.00) | GRM8GRM6GRM7GRM4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115955980-A | Variable charge joint | 思进公司 | 2023-04-11 | — | — | CN | disclosed |
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| US-6013792-A | INTERSTITIAL COLLAGENASE INHIBITOR; ANTIARTHRITIC AGENTS, ANTIOSTEOPOROSIS AGENTS | SYNTEX (U.S.A.), INC. (US) | 2000-01-11 | — | — | US | disclosed |
| WO-1999020785-A1 | PRODUCTION OF GLUTAMATE USING WILD TYPE BACILLUS METHANOLICUS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1999-04-29 | — | — | WO | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |