Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 11/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.59 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948632 | 0.82 | PTGIR (0.66) | PTGIRTBXA2RPSMB8PSMB5KDM4E | |
| SCHEMBL7956621 | 0.78 | PTGIR (0.85) | PTGIRTBXA2RMAPTKDM4EALDH1A1 | |
| SCHEMBL7965750 | 0.76 | PTGIR (0.52) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7959451 | 0.75 | PTGIR (1.00) | PTGIRTBXA2RPSMB8PSMB5KDM4E | |
| SCHEMBL7948777 | 0.73 | PTGIR (0.58) | PTGIRTBXA2RPSMB8PSMB5KDM4E | |
| SCHEMBL7958820 | 0.73 | PTGIR (0.58) | PTGIRTBXA2RPSMB8PSMB5KDM4E | |
| SCHEMBL7956720 | 0.73 | PTGIR (0.58) | PTGIRTBXA2RPSMB8PSMB5KDM4E | |
| SCHEMBL7958794 | 0.72 | PTGIR (0.60) | PTGIRTBXA2RPSMB8PSMB5KDM4E | |
| SCHEMBL7960566 | 0.72 | PTGIR (0.66) | PTGIRTBXA2RKDM4EALDH1A1HPGD | |
| SCHEMBL7956276 | 0.72 | PTGIR (1.00) | PTGIRTBXA2RPSMB8PSMB5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |