Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 13/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13806251 | 0.81 | APP (0.67) | MAPTAPPGLAGAASULT1A1 | |
| SCHEMBL12808066 | 0.77 | APP (0.70) | MAPTAPPGLAGAASULT1A1 | |
| SCHEMBL13453288 | 0.77 | APP (0.70) | MAPTAPPGLAGAASULT1A1 | |
| SCHEMBL796258 | 0.77 | APP (0.60) | MAPTAPPGLAGAASULT1A1 | |
| SCHEMBL796250 | 0.76 | APP (0.69) | MAPTAPP | |
| SCHEMBL13806252 | 0.76 | APP (0.66) | MAPTAPPGLAGAASULT1A1 | |
| SCHEMBL12207300 | 0.75 | APP (0.64) | MAPTAPPGLAGAA | |
| SCHEMBL21566006 | 0.73 | APP (0.57) | MAPTAPP | |
| SCHEMBL17953937 | 0.72 | APP (0.73) | MAPTAPPGLAGAA | |
| SCHEMBL1986282 | 0.72 | APP (0.61) | MAPTAPPGLAGAASULT1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070374-A1 | Compounds for Non-Invasive Measurement of Aggregates of Amyloid Peptides | TECHNISCHE UNIVERSITAT MUNCHEN (DE) | 2012-03-22 | — | — | US | disclosed |
| US-20120070374-A1 | Compounds for Non-Invasive Measurement of Aggregates of Amyloid Peptides | TECHNISCHE UNIVERSITAT MUNCHEN (DE) | 2012-03-22 | — | — | US | disclosed |
| WO-2010092111-A2 | COMPOUNDS FOR NON-INVASIVE MEASUREMENT OF AGGREGATES OF AMYLOID PEPTIDES | Technische Universität München (DE) | 2010-08-19 | — | — | WO | disclosed |
| EP-2218464-A1 | Compounds for non-invasive measurement of aggregates of amyloid peptides | Technische Universität München (DE) | 2010-08-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070374-A1 | Compounds for Non-Invasive Measurement of Aggregates of Amyloid Peptides | IAPP, APP, HTT | MAPT 10/4885APP 2/4885GLA 254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.