Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | RHOC | P08134 | 1/20 | 0.37 |
| ▸ | RHOA | P61586 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075519 | 0.85 | NPC1 (0.49) | RHOCRHOAHDAC3HDAC1ALDH1A1 | |
| SCHEMBL7977366 | 0.85 | NPC1 (0.48) | RHOCRHOAHDAC3HDAC1ALDH1A1 | |
| SCHEMBL8060916 | 0.84 | HPGD (0.51) | HDAC3HDAC1HTTALDH1A1HPGD | |
| SCHEMBL8065540 | 0.83 | NPC1 (0.51) | RHOCRHOAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8077400 | 0.83 | MAPT (0.47) | RHOCRHOAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7981982 | 0.82 | HDAC3 (0.42) | MCL1RHOCRHOAHDAC3HDAC1 | |
| SCHEMBL8061945 | 0.82 | KMT2A (0.47) | RHOCRHOAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8051038 | 0.82 | MCHR1 (0.48) | RHOCRHOAHDAC3HDAC1HTT | |
| SCHEMBL7976340 | 0.82 | NPC1 (0.45) | RHOCRHOAHDAC3HDAC1ALDH1A1 | |
| SCHEMBL7965943 | 0.82 | MCHR1 (0.38) | RHOCRHOAHDAC3HDAC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214835-B1 | CONTROLLING INSECTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0824514-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2000-09-06 | — | — | EP | disclosed |
| WO-1996033160-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-10-24 | — | — | WO | disclosed |