Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 19/20 | 0.60 |
| ▸ | HRH1 | P35367 | 19/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965960 | 0.89 | HRH2 (0.64) | HRH2HRH1HRH3 | |
| SCHEMBL7980042 | 0.85 | HRH2 (0.69) | HRH2HRH1HRH3 | |
| SCHEMBL7245464 | 0.83 | HRH2 (0.66) | HRH2HRH1HRH3 | |
| SCHEMBL7979622 | 0.81 | HRH2 (0.71) | HRH2HRH1HRH3 | |
| SCHEMBL7979448 | 0.78 | HRH2 (0.70) | HRH2HRH1HRH3 | |
| SCHEMBL7965988 | 0.78 | HRH2 (0.62) | HRH2HRH1HRH3 | |
| SCHEMBL7249365 | 0.78 | HRH2 (0.63) | HRH2HRH1HRH3 | |
| SCHEMBL7251638 | 0.77 | HRH2 (0.72) | HRH2HRH1HRH3 | |
| SCHEMBL17712392 | 0.77 | DPP7 (0.41) | — | |
| SCHEMBL7252288 | 0.76 | HRH2 (0.77) | HRH2HRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001066534-A2 | CYCLIC AND BICYCLIC DIAMINO HISTAMINE-3 RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2001-09-13 | — | — | WO | claimed |