Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.70 |
| ▸ | PPARG | P37231 | 12/20 | 0.70 |
| ▸ | PPARD | Q03181 | 14/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6739034 | 0.93 | PPARG (0.79) | PPARAPPARGPPARD | |
| SCHEMBL6739037 | 0.93 | PPARG (0.79) | PPARAPPARGPPARD | |
| SCHEMBL7965108 | 0.91 | PPARA (0.57) | PPARAPPARGPPARD | |
| SCHEMBL7968916 | 0.90 | PPARG (0.65) | PPARAPPARGPPARD | |
| SCHEMBL7968118 | 0.89 | PPARA (0.54) | PPARAPPARGPPARD | |
| SCHEMBL7953586 | 0.84 | PPARA (0.49) | PPARAPPARGPPARD | |
| SCHEMBL6735155 | 0.84 | PPARG (0.66) | PPARAPPARGPPARD | |
| SCHEMBL6735153 | 0.84 | PPARG (0.66) | PPARAPPARGPPARD | |
| SCHEMBL6731786 | 0.82 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL6736232 | 0.81 | PPARA (0.91) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300339-B1 | USEFUL FOR THRERAPY AND/OR PROPHYLAXIS OF INSULIN RESISTANCE (TYPE 2 DIABETES), IMPAIRED GLUCOSE TOLERANCE, DYSLIPIDEMIA, HYPERTENSION, OBESITY, INSULIN RESISTANCE, HYPERGLYCEMIA, ATHEROSCLEROSIS, HYPERLIPIDEMIA, CORONARY ARTERY DISEASE | NOVO NORDISK A/S (DK) | 2001-10-09 | — | — | US | disclosed |