Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 14/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6486203 | 0.79 | EPHX2 (0.47) | EPHX2KDM4EALDH1A1POLB | |
| SCHEMBL25991218 | 0.71 | KMT2A (0.53) | EPHX2KDM4EALDH1A1POLB | |
| SCHEMBL12677070 | 0.66 | CHRM4 (0.61) | P2RY1EPHX2 | |
| SCHEMBL22103767 | 0.66 | EPHX2 (0.86) | P2RY1EPHX2STING1 | |
| SCHEMBL2872773 | 0.66 | IDO1 (0.56) | P2RY1EPHX2STING1 | |
| SCHEMBL11555827 | 0.66 | EPHX2 (1.00) | EPHX2STING1ALDH1A1 | |
| SCHEMBL22263059 | 0.66 | MEN1 (0.72) | P2RY1EPHX2STING1KDM4EPOLB | |
| SCHEMBL17079593 | 0.66 | EPHX2 (0.69) | P2RY1EPHX2STING1 | |
| SCHEMBL2872598 | 0.66 | EPHX2 (0.69) | P2RY1EPHX2STING1 | |
| SCHEMBL6702924 | 0.66 | CCR3 (0.82) | CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068604-A2 | 3-SUBSTITUTED PIPERIDINES COMPRISING UREA FUNCTIONALITY, AND METHODS OF USE THEREOF | SEPRACOR, INC. (US) | 2001-09-20 | — | — | WO | disclosed |