Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 3/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963223 | 1.00 | ELANE (0.53) | ELANEABCB1KLK7RORCPOLB | |
| SCHEMBL3082634 | 0.87 | ELANE (0.48) | ELANEABCB1KLK7RORCGPR119 | |
| SCHEMBL3082629 | 0.87 | ELANE (0.48) | ELANEABCB1KLK7RORCGPR119 | |
| SCHEMBL3082637 | 0.87 | ELANE (0.48) | ELANEABCB1KLK7RORCGPR119 | |
| SCHEMBL15432888 | 0.83 | ELANE (0.44) | ELANEABCB1KLK7RORCGPR119 | |
| SCHEMBL15432894 | 0.83 | ELANE (0.44) | ELANEABCB1KLK7RORCGPR119 | |
| SCHEMBL3082464 | 0.83 | ELANE (0.49) | ELANEABCB1KLK7RORCGPR119 | |
| SCHEMBL3083528 | 0.83 | ELANE (0.49) | ELANEABCB1KLK7RORCGPR119 | |
| SCHEMBL13139159 | 0.83 | ELANE (0.49) | ELANEABCB1KLK7RORCGPR119 | |
| SCHEMBL3083530 | 0.83 | ELANE (0.49) | ELANEABCB1KLK7RORCGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218553-B1 | METALLIZATION BY REACTING A BACCATIN III DERIVATIVE WITH A METAL ALKYLDISILAZIDE | THE STATE UNIVERSITY OF NEW YORK AT STONY BROOK | 2001-04-17 | — | — | US | disclosed |