Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 6/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789787 | 1.00 | SLC1A1 (0.51) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 | |
| SCHEMBL7977999 | 0.81 | SLC1A3 (0.60) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 | |
| SCHEMBL7784358 | 0.79 | SLC1A3 (0.51) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 | |
| SCHEMBL7792911 | 0.77 | SLC1A3 (0.51) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 | |
| SCHEMBL28794235 | 0.76 | SLC1A3 (0.50) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 | |
| SCHEMBL2037092 | 0.76 | SLC1A3 (0.50) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 | |
| SCHEMBL7900106 | 0.76 | SLC1A3 (0.50) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL4867826 | 0.75 | SLC1A3 (0.49) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 | |
| SCHEMBL3653035 | 0.75 | SLC1A3 (0.49) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 | |
| SCHEMBL6167905 | 0.74 | PPARG (0.54) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291687-B1 | USED ASPARTYL PROTEASE INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) | MEDIVIR AB (SE) | 2001-09-18 | — | — | US | disclosed |