Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977057 | 1.00 | CYP4F2 (0.43) | CYP4F2CYP4A11ITGB3ITGA2BPOLB | |
| SCHEMBL7967375 | 1.00 | CYP4F2 (0.43) | CYP4F2CYP4A11ITGB3ITGA2BPOLB | |
| SCHEMBL7979003 | 0.89 | CYP4F2 (0.46) | CYP4F2CYP4A11ITGB3ITGA2BPOLB | |
| SCHEMBL6954907 | 0.82 | CYP4F2 (0.48) | CYP4F2CYP4A11MIFDRD3DRD2 | |
| SCHEMBL7981034 | 0.81 | CYP4F2 (0.47) | CYP4F2CYP4A11ITGB3ITGA2BMIF | |
| SCHEMBL6307386 | 0.81 | CYP4F2 (0.47) | CYP4F2CYP4A11ITGB3ITGA2BMIF | |
| SCHEMBL5640207 | 0.81 | CYP4F2 (0.47) | CYP4F2CYP4A11ITGB3ITGA2BGLA | |
| SCHEMBL6745996 | 0.81 | CYP4F2 (0.47) | CYP4F2CYP4A11ITGB3ITGA2BMIF | |
| Hydrochloric Acid SCHEMBL6744719 | 0.80 | CYP4F2 (0.46) | CYP4F2CYP4A11ITGB3ITGA2BMIF | |
| Hydrochloric Acid SCHEMBL7980574 | 0.80 | CYP4F2 (0.46) | CYP4F2CYP4A11ITGB3ITGA2BMIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087871-A2 | METHODS FOR PRODUCING AMINO SUBSTITUTED CHROMANES AND INTERMEDIATES THEREFOR | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2001-11-22 | — | — | WO | disclosed |