Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 10/20 | 0.43 |
| ▸ | HTR2B | P41595 | 7/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32677827 | 1.00 | GAA (1.00) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7982332 | 1.00 | GAA (1.00) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7985244 | 1.00 | GAA (1.00) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29978990 | 0.95 | GAA (0.90) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15523034 | 0.93 | GAA (0.88) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL15522726 | 0.79 | GAA (0.66) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL30729380 | 0.78 | MEN1 (0.64) | GAAMEN1KMT2AHTR2CHTR2B | |
| SCHEMBL26092480 | 0.78 | GAA (0.64) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL30910113 | 0.78 | GAA (0.64) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3260203 | 0.78 | MEN1 (0.64) | GAAMEN1KMT2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225306-B1 | PYRROLO(1,2A)QUINOXALINES | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-01 | — | — | US | disclosed |
| EP-0987266-A1 | BIPHENYL DERIVATIVES AND MEDICINAL COMPOSITIONS | Wakamoto Pharmaceutical Co., Ltd. (JP) | 2000-03-22 | — | — | EP | disclosed |