Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968626 | 1.00 | KDM4E (0.49) | KDM4EMAPTL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL5357801 | 0.76 | KDM4E (0.54) | KDM4EMAPTL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL5357804 | 0.76 | KDM4E (0.54) | KDM4EMAPTL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL5362550 | 0.75 | KDM4E (0.59) | KDM4EMAPTL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL5357627 | 0.75 | KDM4E (0.59) | KDM4EMAPTL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL14985433 | 0.74 | MEN1 (0.57) | KDM4EMAPTL3MBTL1NPC1MEN1 | |
| SCHEMBL684865 | 0.74 | KDM4E (0.74) | KDM4EMAPTL3MBTL1NPC1MEN1 | |
| SCHEMBL5358192 | 0.73 | MAPT (0.64) | KDM4EMAPTL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL5358196 | 0.73 | MAPT (0.64) | KDM4EMAPTL3MBTL1ALDH1A1NPC1 | |
| SCHEMBL11407707 | 0.73 | MEN1 (0.58) | KDM4EMAPTALDH1A1NPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329378-B1 | HETEROCYCLIC FUNGICIDES AND ANTIGROWTH AGENTS | ANADYS PHARMACEUTICALS, INC. | 2001-12-11 | — | — | US | disclosed |