Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1465120 | 0.85 | CYP19A1 (0.54) | CYP19A1HRH4POLBMAPTMAOB | |
| SCHEMBL31735948 | 0.85 | CYP19A1 (0.54) | CYP19A1HRH4POLBMAPTMAOB | |
| SCHEMBL3962934 | 0.80 | CYP19A1 (0.49) | CYP19A1HRH4POLBMAPTMAOB | |
| SCHEMBL12824816 | 0.80 | CYP19A1 (0.49) | CYP19A1HRH4POLBMAPTMAOB | |
| SCHEMBL1465991 | 0.79 | CYP19A1 (0.48) | CYP19A1HRH4POLBMAPTMAOB | |
| SCHEMBL12825163 | 0.79 | CYP19A1 (0.51) | CYP19A1HRH4POLBMAPTMAOB | |
| SCHEMBL1465132 | 0.77 | CYP19A1 (0.44) | CYP19A1HRH4POLBMAPTMAOB | |
| SCHEMBL6609186 | 0.74 | CYP2A6 (0.51) | HRH4MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22529388 | 0.74 | CYP19A1 (0.42) | CYP19A1HRH4POLBNOS1MEN1 | |
| SCHEMBL1465403 | 0.74 | CYP19A1 (0.45) | CYP19A1HRH4POLBMAPTCRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242470-B1 | RHEUMATIC DISEASES; ANTIARTHRITIC AGENTS, ANTIALLERGENS; IRRITABLE BOWEL SYNDROME; AMIDATION | ASTRAZENECA AB (SE) | 2001-06-05 | — | — | US | disclosed |