Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 18/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970505 | 0.90 | LCK (0.67) | LCKMAPTATMTDP1L3MBTL1 | |
| SCHEMBL7983663 | 0.82 | LCK (0.65) | LCKMAPTATMTDP1L3MBTL1 | |
| SCHEMBL4931040 | 0.82 | LCK (1.00) | LCK | |
| SCHEMBL7970323 | 0.81 | LCK (0.67) | LCK | |
| SCHEMBL7970845 | 0.80 | LCK (0.80) | LCK | |
| SCHEMBL7981428 | 0.80 | LCK (0.80) | LCK | |
| SCHEMBL7969645 | 0.80 | LCK (0.84) | LCK | |
| SCHEMBL7969769 | 0.80 | LCK (0.84) | LCK | |
| SCHEMBL7980236 | 0.77 | LCK (0.74) | LCKMAPT | |
| SCHEMBL7981168 | 0.77 | LCK (0.78) | LCKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | claimed |
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |