Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970637 | 0.84 | RHEB (0.41) | KDM4ESMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL10139885 | 0.83 | MAPT (0.60) | KDM4ESMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL7970842 | 0.81 | NPC1 (0.55) | KDM4ESMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL7976170 | 0.81 | ITK (0.48) | KDM4ESMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL10139808 | 0.81 | P2RY6 (0.53) | KDM4ESMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL10140103 | 0.80 | F9 (0.39) | KDM4ESMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL7971018 | 0.79 | HSD17B10 (0.37) | KDM4ESMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL7970459 | 0.78 | KDM4E (0.40) | KDM4ESMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL10139913 | 0.78 | F9 (0.43) | KDM4ESMN1; SMN2NPC1RAB9ATP53 | |
| SCHEMBL7972135 | 0.77 | PDE10A (0.37) | SMN1; SMN2NPC1RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |