Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 20/20 | 0.57 |
| ▸ | ITGB2 | P05107 | 19/20 | 0.57 |
| ▸ | ICAM1 | P05362 | 19/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709464 | 1.00 | ITGAL (0.57) | ITGALITGB2ICAM1 | |
| SCHEMBL5239341 | 0.84 | ITGAL (0.80) | ITGALITGB2ICAM1 | |
| SCHEMBL5203942 | 0.84 | ITGAL (0.80) | ITGALITGB2ICAM1 | |
| SCHEMBL7706514 | 0.82 | ITGAL (0.60) | ITGALITGB2ICAM1 | |
| SCHEMBL7130481 | 0.75 | ITGB2 (0.62) | ITGALITGB2ICAM1 | |
| SCHEMBL5204304 | 0.75 | ITGB2 (0.62) | ITGALITGB2ICAM1 | |
| SCHEMBL4854343 | 0.74 | ITGAL (0.41) | ITGALITGB2ICAM1 | |
| SCHEMBL5206070 | 0.74 | ITGAL (0.80) | ITGALITGB2ICAM1 | |
| SCHEMBL5206081 | 0.74 | ITGAL (0.80) | ITGALITGB2ICAM1 | |
| SCHEMBL5203590 | 0.73 | ITGAL (1.00) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007048-A1 | SMALL MOLECULES USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASE | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-02-01 | — | — | WO | disclosed |