SCHEMBL7970464

SCHEMBL7970464

CS(=O)(=O)c1ccccc1C(=O)n1c2cc(O)c(O)cc2c2ccc(O)c(O)c21

nearest known ligand 0.64

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SRC P12931 20/20 0.64
PRKACA P17612 13/20 0.64
PRKACG P22612 13/20 0.64
PRKACB P22694 13/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7981703 0.82 SRC (0.67) SRCPRKACAPRKACGPRKACB
SCHEMBL7987341 0.79 SRC (0.64) SRCPRKACAPRKACGPRKACB
SCHEMBL7984723 0.78 SRC (1.00) SRCPRKACAPRKACGPRKACB
SCHEMBL7970463 0.78 SRC (1.00) SRCPRKACAPRKACGPRKACB
SCHEMBL7987588 0.74 SRC (1.00) SRCPRKACAPRKACGPRKACB
SCHEMBL7984287 0.74 SRC (1.00) SRCPRKACAPRKACGPRKACB
SCHEMBL7983687 0.73 SRC (1.00) SRCPRKACAPRKACGPRKACB
SCHEMBL7987590 0.71 SRC (1.00) SRCPRKACAPRKACGPRKACB
SCHEMBL7987642 0.69 SRC (0.65) SRCPRKACAPRKACGPRKACB
SCHEMBL7980278 0.68 SRC (1.00) SRCPRKACAPRKACGPRKACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6194439-B1 ANTICANCER AGENT PFIZER INC. 2001-02-27 US disclosed
WO-1992021660-A1 TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS PFIZER, INC. (US) 1992-12-10 WO disclosed