Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140093 | 0.87 | TP53 (0.38) | AMY1AKDM4EHSD17B10TP53ALDH1A1 | |
| SCHEMBL10172619 | 0.87 | DHODH (0.39) | AMY1AKDM4EHSD17B10TP53ALDH1A1 | |
| SCHEMBL10140097 | 0.85 | DHODH (0.41) | KDM4EHSD17B10TP53ALDH1A1HPGD | |
| SCHEMBL7982191 | 0.83 | P2RY6 (0.51) | KDM4EHSD17B10TP53ALDH1A1HPGD | |
| SCHEMBL10139799 | 0.82 | NPC1 (0.65) | KDM4EHSD17B10TP53ALDH1A1HPGD | |
| SCHEMBL7959879 | 0.81 | KDM4E (0.40) | AMY1AKDM4EHSD17B10TP53ALDH1A1 | |
| SCHEMBL7961586 | 0.79 | CHEK2 (0.53) | KDM4EALDH1A1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL7966178 | 0.78 | NPC1 (0.65) | KDM4EHSD17B10TP53ALDH1A1HPGD | |
| SCHEMBL10140405 | 0.78 | CHEK2 (0.48) | KDM4EHSD17B10TP53ALDH1A1HPGD | |
| SCHEMBL7960793 | 0.77 | KDM4E (0.52) | KDM4EHSD17B10TP53ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |