Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PAM | P19021 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11598732 | 1.00 | KMT2A (0.54) | KMT2ACYP1A2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL25212852 | 0.93 | KMT2A (0.51) | KMT2ACYP1A2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL15028249 | 0.93 | KMT2A (0.51) | KMT2ACYP1A2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL11528078 | 0.92 | CYP1A2 (0.55) | KMT2ACYP1A2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL4800391 | 0.91 | KMT2A (0.50) | KMT2ACYP1A2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL11614940 | 0.91 | KMT2A (0.50) | KMT2ACYP1A2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL24715407 | 0.91 | KMT2A (0.50) | KMT2ACYP1A2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL11654967 | 0.90 | KMT2A (0.49) | KMT2ACYP1A2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL11514409 | 0.89 | CYP1A2 (0.52) | KMT2ACYP1A2TDP1ALDH1A1CYP3A4 | |
| SCHEMBL4835509 | 0.89 | CYP1A2 (0.52) | KMT2ACYP1A2TDP1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |
| EP-0968164-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998033758-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-06 | — | — | WO | disclosed |