Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.62 |
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692801 | 0.88 | KDR (0.72) | KDREGLN1ALDH1A1KDM4EMAPT | |
| Methane SCHEMBL7688532 | 0.87 | EGLN1 (0.67) | KDREGLN1ALDH1A1MEN1KMT2A | |
| SCHEMBL7692160 | 0.85 | KDR (0.74) | KDREGLN1ALDH1A1MEN1KMT2A | |
| SCHEMBL7691465 | 0.83 | KDR (0.71) | KDREGLN1ALDH1A1MEN1KMT2A | |
| SCHEMBL7691468 | 0.82 | KDR (0.57) | KDREGLN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL7686901 | 0.81 | EGLN1 (0.68) | KDREGLN1ALDH1A1MEN1KMT2A | |
| SCHEMBL7686473 | 0.80 | EGLN1 (0.67) | KDREGLN1ALDH1A1MEN1KMT2A | |
| SCHEMBL7684395 | 0.79 | EGLN1 (0.70) | KDREGLN1ALDH1A1MEN1KMT2A | |
| SCHEMBL7686843 | 0.79 | EGLN1 (0.62) | KDREGLN1ALDH1A1MEN1KMT2A | |
| SCHEMBL7688530 | 0.79 | EGLN1 (0.65) | KDREGLN1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310211-B1 | ANTI-VIRAL ACTIVITY AGAINST HERPES VIRUS, CYTOMEGALOVIRUS. MANY OF THESE COMPOUNDS ARE ALSO ACTIVE AGAINST VARICELLA ZOSTER VIRUS, EPSTEIN-BARR VIRUS, HERPES SIMPLEX VIRUS AND HUMAN HERPES VIRUS TYPE 8 | PHARMACIA & UPJOHN COMPANY | 2001-10-30 | — | — | US | disclosed |