Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 5/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95949 | 0.84 | MAOB (0.50) | MAOBAPPMAOA | |
| SCHEMBL920100 | 0.83 | MAOB (0.53) | MAOBAPPMAOACA12CA1 | |
| SCHEMBL921156 | 0.83 | MAOB (0.50) | MAOBAPPMAOASMPD1 | |
| SCHEMBL920275 | 0.83 | MAOB (0.54) | MAOBAPPMAOA | |
| SCHEMBL27810352 | 0.81 | MAOB (0.51) | MAOBAPPMAOA | |
| SCHEMBL921127 | 0.81 | APP (0.53) | MAOBAPPSMPD1 | |
| SCHEMBL920026 | 0.80 | MAOB (0.60) | MAOBAPPMAOASMPD1 | |
| SCHEMBL921839 | 0.79 | SMN1; SMN2 (0.42) | APP | |
| SCHEMBL2901614 | 0.79 | MAOB (0.54) | MAOBMAOA | |
| SCHEMBL6154800 | 0.79 | APP (0.54) | MAOBAPPRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265408-B1 | PSYCHOLOGICAL DISORDERS; ANTIDEPRESSANT | SMITHKLINE BEECHAM PLC (GB) | 2001-07-24 | — | — | US | disclosed |