Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QRFPR | Q96P65 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7598799 | 0.99 | QRFPR (0.46) | QRFPRKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL7599901 | 0.92 | QRFPR (0.46) | QRFPRKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL7600936 | 0.90 | QRFPR (0.48) | QRFPRKMT2AMEN1ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL7598592 | 0.89 | QRFPR (0.47) | QRFPRKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL7598787 | 0.89 | KMT2A (0.39) | QRFPRKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL7597196 | 0.88 | ATM (0.39) | QRFPRKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL7602422 | 0.87 | QRFPR (0.36) | QRFPRKMT2AMEN1ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL7599078 | 0.87 | ATM (0.38) | QRFPRKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL7598660 | 0.86 | CARM1 (0.44) | QRFPRKMT2AMEN1ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL7599408 | 0.86 | QRFPR (0.35) | QRFPRKMT2AMEN1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001046171-A1 | AMIDINE DERIVATIVES WHICH ARE INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2001-06-28 | — | — | WO | claimed |
| WO-2001046171-A1 | AMIDINE DERIVATIVES WHICH ARE INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2001-06-28 | — | — | WO | disclosed |