Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 14/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 9/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | CASR | P41180 | 3/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971748 | 1.00 | ADRB3 (0.50) | ADRB3ADRB1ADRB2CYP2D6CASR | |
| SCHEMBL7746703 | 0.92 | ADRB3 (0.49) | ADRB3ADRB1ADRB2CYP2D6CASR | |
| SCHEMBL7746708 | 0.92 | ADRB3 (0.49) | ADRB3ADRB1ADRB2CYP2D6CASR | |
| SCHEMBL6387352 | 0.88 | ADRB3 (0.51) | ADRB3ADRB1ADRB2CYP2D6CASR | |
| SCHEMBL6387355 | 0.88 | ADRB3 (0.51) | ADRB3ADRB1ADRB2CYP2D6CASR | |
| SCHEMBL7971740 | 0.84 | ADRB3 (0.53) | ADRB3ADRB1ADRB2CYP2D6CASR | |
| SCHEMBL6393871 | 0.84 | ADRB3 (0.55) | ADRB3ADRB1ADRB2CYP2D6CASR | |
| SCHEMBL6393880 | 0.84 | ADRB3 (0.55) | ADRB3ADRB1ADRB2CYP2D6CASR | |
| SCHEMBL7746700 | 0.84 | ADRB3 (0.49) | ADRB3ADRB1ADRB2CYP2D6CASR | |
| SCHEMBL7973558 | 0.82 | ADRB3 (0.54) | ADRB3ADRB1ADRB2CYP2D6CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001036412-A1 | PROCESS FOR THE PREPARATION OF ARYLOXY PROPANOLAMINES | ELI LILLY AND COMPANY (US) | 2001-05-25 | — | — | WO | disclosed |