Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977045 | 0.86 | NPSR1 (0.46) | THRBATML3MBTL1NPSR1MMP1 | |
| SCHEMBL8976976 | 0.86 | NPSR1 (0.46) | THRBATML3MBTL1NPSR1MMP1 | |
| SCHEMBL11412912 | 0.81 | SMN1; SMN2 (0.57) | THRBATML3MBTL1NPSR1MMP1 | |
| SCHEMBL9865762 | 0.81 | SMN1; SMN2 (0.57) | THRBATML3MBTL1NPSR1MMP1 | |
| SCHEMBL8393517 | 0.80 | EPHX1 (0.60) | THRBATML3MBTL1NPSR1MMP1 | |
| SCHEMBL20350198 | 0.80 | EPHX1 (0.60) | THRBATML3MBTL1NPSR1MMP1 | |
| SCHEMBL2802318 | 0.80 | EPHX1 (0.60) | THRBATML3MBTL1NPSR1MMP1 | |
| SCHEMBL11518690 | 0.79 | EPHX1 (0.51) | THRBATML3MBTL1NPSR1MMP1 | |
| Hydrochloric Acid SCHEMBL4535556 | 0.79 | EPHX1 (0.58) | THRBATML3MBTL1NPSR1MMP1 | |
| SCHEMBL20827027 | 0.79 | SMN1; SMN2 (0.54) | THRBATML3MBTL1NPSR1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281295-B1 | Enamines as vulcanization accelerators for natural or synthetic rubbers | GREAT LAKES CHEMICAL ITALIA S.R.L. (IT) | 2001-08-28 | — | — | US | disclosed |
| EP-0735083-B1 | Enamines as vulcanization accelerators for natural or synthetic rubbers | GREAT LAKES CHEMICAL EUROP (CH) | 2000-02-09 | — | — | EP | disclosed |
| EP-0735083-A1 | Enamines as vulcanization accelerators for natural or synthetic rubbers | GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) | 1996-10-02 | — | — | EP | disclosed |