Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 5/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.37 |
| ▸ | MAP3K7 | O43318 | 4/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7966140 | 0.99 | AVPR2 (0.36) | AVPR2AVPR1AAVPR1BMAP3K7BRD4 | |
| Hydrochloric Acid SCHEMBL7485435 | 0.97 | AVPR2 (0.36) | AVPR2AVPR1AAVPR1BMAP3K7BRD4 | |
| SCHEMBL7962035 | 0.95 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1BMAP3K7BRD4 | |
| Hydrochloric Acid SCHEMBL7964741 | 0.95 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1BMAP3K7BRD4 | |
| SCHEMBL7953928 | 0.95 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1BMAP3K7BRD4 | |
| SCHEMBL7487329 | 0.95 | AVPR2 (0.38) | AVPR2AVPR1AAVPR1BMAP3K7BRD4 | |
| SCHEMBL7483216 | 0.94 | AVPR2 (0.38) | AVPR2AVPR1AAVPR1BMAP3K7BRD4 | |
| Hydrochloric Acid SCHEMBL7964657 | 0.94 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1BMAP3K7BRD4 | |
| Hydrochloric Acid SCHEMBL7963173 | 0.94 | AVPR2 (0.38) | AVPR2AVPR1AAVPR1BMAP3K7BRD4 | |
| SCHEMBL7598670 | 0.94 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BMAP3K7BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207693-B1 | Benzamide derivatives having a vasopressin antagonistic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |