Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | UNG | P13051 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959238 | 0.75 | KCNN4 (0.44) | LMNAHDAC1HDAC2ALDH1A1KDM4E | |
| SCHEMBL7972466 | 0.74 | KCNN4 (0.43) | LMNAHDAC1HDAC2NPC1RAB9A | |
| SCHEMBL7959265 | 0.73 | ATM (0.48) | LMNAHDAC1HDAC2FAAHNPC1 | |
| SCHEMBL8420258 | 0.73 | ATM (0.48) | LMNAHDAC1HDAC2FAAHNPC1 | |
| SCHEMBL23992348 | 0.71 | SMN1; SMN2 (0.69) | LMNAHDAC1HDAC2NPC1RAB9A | |
| SCHEMBL7975610 | 0.69 | KCNN4 (0.34) | HDAC1HDAC2ATMKDM4EMEN1 | |
| SCHEMBL24265020 | 0.69 | NPC1 (0.43) | LMNAHDAC1HDAC2FAAHNPC1 | |
| SCHEMBL12495523 | 0.68 | CYP2C9 (0.52) | LMNANPC1RAB9AATMALDH1A1 | |
| SCHEMBL2028143 | 0.68 | KCNN4 (0.43) | LMNAHDAC1HDAC2ALDH1A1MEN1 | |
| SCHEMBL7969298 | 0.68 | MEN1 (0.46) | LMNAALDH1A1SMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313150-B1 | FOR CONTROLLING PHYTOPATHOGENIC FUNGI | SHIONOGI & CO., LTD. (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-0754672-B1 | GAMMA-SUBSTITUTED PHENYLACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND AGRICULTURAL BACTERICIDE CONTAINING THE SAME | SHIONOGI & CO (JP) | 2000-10-11 | — | — | EP | disclosed |
| US-5948819-A | α-substituted phenylacetic acid derivative, its production and agricultural fungicide containing it | SHIONOGI & CO., LTD (JP) | 1999-09-07 | — | — | US | disclosed |
| EP-0754672-A1 | GAMMA-SUBSTITUTED PHENYLACETIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND AGRICULTURAL BACTERICIDE CONTAINING THE SAME | SHIONOGI & CO., LTD. (JP) | 1997-01-22 | — | — | EP | disclosed |