Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL275394 | 0.77 | SYK (0.58) | TACR1ALDH1A1SYKPPARA | |
| SCHEMBL6704067 | 0.77 | SYK (0.58) | TACR1ALDH1A1SYKPPARA | |
| SCHEMBL2955816 | 0.77 | SYK (0.58) | TACR1ALDH1A1SYKPPARA | |
| SCHEMBL20783244 | 0.76 | CYP1A2 (0.47) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL2393366 | 0.76 | CYP1A2 (0.47) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL25256775 | 0.76 | CYP1A2 (0.47) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| Hydrochloric Acid SCHEMBL7444525 | 0.76 | SYK (0.57) | TACR1ALDH1A1SYKPPARA | |
| Hydrochloric Acid SCHEMBL7444521 | 0.76 | SYK (0.57) | TACR1ALDH1A1SYKPPARA | |
| Hydrochloric Acid SCHEMBL17686459 | 0.75 | CYP1A2 (0.46) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| Hydrochloric Acid SCHEMBL14471495 | 0.75 | CYP1A2 (0.46) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274620-B1 | 2-BENZENESULFONYLAMINO-3-((5-BROMO-THIOPHENE-2-CARBONYL)-AMINO )PROPIONIC ACID-TERT-BUTYL ESTERS AS ANGIOGENESIS INHIBITORS; ANTICARCINOGENIC AGENTS; OSTEOPOROSIS, RESTENOSIS, AND OCULAR NEOVASCULARIZATION | BIOCHEM PHARMA INC. (CA) | 2001-08-14 | — | — | US | disclosed |