Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 8/20 | 0.51 |
| ▸ | NPY1R | P25929 | 6/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.51 |
| ▸ | NPY2R | P49146 | 2/20 | 0.51 |
| ▸ | GLP1R | P43220 | 4/20 | 0.50 |
| ▸ | SCTR | P47872 | 1/20 | 0.50 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.50 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.50 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972947 | 1.00 | NPY4R (0.51) | NPY4RNPY1RNPY5RNPY2RGLP1R | |
| SCHEMBL31388270 | 0.90 | NPY4R (0.64) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL31064947 | 0.90 | BACE1 (0.55) | NPY4RNPY1RNPY5RNPY2RGLP1R | |
| SCHEMBL30845345 | 0.90 | NPY4R (0.47) | NPY4RNPY1RNPY5RNPY2RGLP1R | |
| SCHEMBL31026560 | 0.89 | NPY4R (0.54) | NPY4RNPY1RNPY5RNPY2RGLP1R | |
| SCHEMBL29531737 | 0.88 | NPY4R (0.51) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL29710470 | 0.88 | C5AR1 (0.50) | NPY4RNPY1RNPY5RNPY2RGLP1R | |
| SCHEMBL30341658 | 0.88 | NPY4R (0.54) | NPY4RNPY1RNPY5RNPY2RTUBB4A | |
| SCHEMBL30605443 | 0.88 | NPY4R (0.54) | NPY4RNPY1RNPY5RNPY2RKISS1R | |
| SCHEMBL30612296 | 0.88 | NPY4R (0.54) | NPY4RNPY1RNPY5RNPY2RKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277558-B1 | DETECTING GOODPASTURE ANTIBODIES IN A BODILY FLUID OR TISSUE VIA CONTACTING WITH ALPHA-3 CHAIN TYPE IV COLLAGEN POLYPEPTIDE WHICH CONTAINS CONFORMATIONAL EPITOPE | KANSAS UNIVERSITY MEDICAL CENTER | 2001-08-21 | — | — | US | disclosed |
| US-6007980-A | A METHOD FOR DETECTING GOODPASTURE ANTIBODIES IN A BIOLOGICAL FLUID SAMPLE BY MIXING FLUID SAMPLE WITH A PEPTIDE WHICH CODES FOR A HUMAN COLLAGEN; ANTIBODIES IN SAMPLE BINDING TO PEPTIDE IN AN IMMUNOASSAY IDICATES ANTIBODIES ARE PRESENT | YALE UNIVERSITY (US) | 1999-12-28 | — | — | US | disclosed |
| US-5973120-A | α-3 chain type IV collagen polypeptides | YALE UNIVERSITY (US) | 1999-10-26 | — | — | US | disclosed |
| US-5424408-A | α-3 chain type IV collagen polynucleotides | YALE UNIVERSITY (US) | 1995-06-13 | — | — | US | disclosed |