Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959886 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2CYP2D6KMT2A | |
| SCHEMBL7973302 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2CYP2D6KMT2A | |
| SCHEMBL7976128 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2CYP2D6KMT2A | |
| SCHEMBL7959881 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2CYP2D6KMT2A | |
| SCHEMBL28860925 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2CYP2D6KMT2A | |
| SCHEMBL7973454 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1SMN1; SMN2CYP2D6KMT2A | |
| SCHEMBL7970980 | 0.95 | KDM4E (0.52) | KDM4EALDH1A1SMN1; SMN2CYP2D6KMT2A | |
| SCHEMBL7959928 | 0.95 | KDM4E (0.52) | KDM4EALDH1A1SMN1; SMN2CYP2D6KMT2A | |
| SCHEMBL7970976 | 0.95 | KDM4E (0.52) | KDM4EALDH1A1SMN1; SMN2CYP2D6KMT2A | |
| SCHEMBL7959933 | 0.95 | KDM4E (0.52) | KDM4EALDH1A1SMN1; SMN2CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |