⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10232118 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL31267354 | 0.97 | — | — | |
| SCHEMBL26765798 | 0.74 | — | — | |
| SCHEMBL12527980 | 0.74 | — | — | |
| SCHEMBL19090073 | 0.74 | — | — | |
| SCHEMBL23998069 | 0.74 | — | — | |
| SCHEMBL19090072 | 0.74 | — | — | |
| SCHEMBL19090075 | 0.74 | — | — | |
| SCHEMBL19090074 | 0.74 | — | — | |
| Propylene Oxide SCHEMBL7866490 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719603-A1 | SPIROCYCLIC ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER | Boehringer Ingelheim International GmbH (DE) | 2026-04-08 | — | — | EP | disclosed |
| US-20250019385-A1 | SPIROCYCLIC ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER | BOEHRINGER INGELHEIM INT (DE) | 2025-01-16 | — | — | US | disclosed |
| WO-2024246099-A1 | SPIROCYCLIC ANNULATED 2-AMINO-3-CYANO THIOPHENES AND DERIVATIVES FOR THE TREATMENT OF CANCER | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-12-05 | — | — | WO | disclosed |
| US-7332509-B2 | Heterocyclic amides, a process for their preparation, compositions comprising them and their use | MERIAL LIMITED (US) | 2008-02-19 | — | — | US | disclosed |
| US-7332509-B2 | Heterocyclic amides, a process for their preparation, compositions comprising them and their use | MERIAL LIMITED (US) | 2008-02-19 | — | — | US | disclosed |
| EP-1434485-B1 | NICOTINIC ACID-HETEROCYCLYL-AMIDES AND ANALOGOUS PYRIMIDINE DERIVATIVES FOR USE AS PESTICIDES | MERIAL LTD (US) | 2007-05-16 | — | — | EP | disclosed |
| US-6207668-B1 | FOR CONTROLLING INSECTS OR THEIR EGGS; AS FUNGICIDES, OVICIDES OR AS VETERINARY MEDICAMENTS | HOECHST SCHERING (DE) | 2001-03-27 | — | — | US | disclosed |
| EP-0892798-A1 | SUBSTITUTED PYRIDINES/PYRIMIDINES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997037991-A1 | SUBSTITUTED PYRIDINES/PYRIMIDINES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1997-10-16 | — | — | WO | disclosed |